Basic Information
VIS ID
TVIS30001180
Fusion event
HIV-chr4 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q34.1
Reference genome
GRCh37/hg19
Start
176010824/175089673 (Hg38)
End
176011685/175089673 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/665809; hsa-mir-1305/Downstream/7079620;
Nearest TSS
ENST00000502981/Upstream/110292; ENST00000514864/Downstream/313437;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/260240, chr4-CpG: 26/Downstream/911649
Nearby gene
ADAM29(No orient, 111493)
Target sequence
CTTAGTCTTTCAGAAATATTTTTATTTTTACTTTGTTGTTTGCTTCACATTCTCTGAATATTGATGTTGCATTTGTTTTGATTAAAAACAAACCAGATTTTTTGTATGAGAAAAATATATCTCAATTTGTTTATGCAGTATTAGGTAGGAATTTTGTGTTTTGCTTTAAAAAATCAATTCAAACTTCTACAATATAATAGACATGAAAGAGAATTTTCTTGAATCTGCATCTATATATGATCTGGCTAATGTCTC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate