Basic Information
VIS ID
TVIS30001182
Fusion event
HIV-LOC105373774 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
184080943/183216215 (Hg38)
End
184081755/183216215 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373774
Nearest miRNA
hsa-mir-10b/Upstream/1910563; hsa-mir-1244-1/Downstream/1162760;
Nearest TSS
ENST00000437798/Upstream/1896; ENST00000441026/Downstream/688314;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/177662, chr2-CpG: 26/Downstream/44400
Nearby gene
NUP35(No orient, 54531)
Target sequence
ATGACCATATATCATAGTCTCTTAGTTTAGTGAATTTCAGGCATCAGTCTGAGGACTTGAGTTGATTTGTGAAGAAATTTCAGCATCTGCTCTCTTAACCTAGTGATTGACTTCCGGGTTTCAAAAAATGGTTCCTACACAACAGCTATTATTATAGATTGCTGTAGGAACTACTCTTTGCAGCCATTTATTAGCACTCGCAGGGCCACTTTCTAATCTTCTGAAGGCTCTTTCTGCATCCATGCTCGTTCTCTC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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