Basic Information
VIS ID
TVIS30001191
Fusion event
HIV-ARHGAP11B integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
30936367/30644164 (Hg38)
End
30937178/30644164 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARHGAP11B
Nearest miRNA
hsa-mir-1268a/Upstream/2153319; hsa-mir-10393/Downstream/420868;
Nearest TSS
ENST00000557528/Upstream/9839; ENST00000602684/Downstream/4633;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/17802, chr15-CpG: 18/Downstream/238928
Target sequence
GCCCCCCACCCACTCTACAGGAAAACTTGCCCAGATCTACAGGAACCTCCCCACACACAAGAGGACAGGGCAGCCCAGACTCATGTCAACAGCTGGCACAAATGAATTACAGATTACTTACAATTCACATAACACTGACCCAAGAATATAACCAATTGTCAAGACAAAATAAATTTAGTTATTCACATACAAATATTCCATTTGTGAATAAATTTCATATTCGTATCTGTATACAGACAGTCTACATGTTCGATA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate