Basic Information
VIS ID
TVIS30001216
Fusion event
HIV-RNASEH2B integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
End
51528634/50953863 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-15a/Upstream/904662; hsa-mir-1267/Downstream/394704;
Target sequence
TATGTGAACATTTTCACAATTTAATGTTAAATAAAAAGCCCAGAACTGAGTATTATAATGCCAATGTTAAAGGCCACATATGTATTTATAATGCATGTATAAAACTAAGTAAGGACTGTTACCAAAATGCCATTTGCCAGGGTGAATGCTGAATGGTGAAATTATTAATTTTTATCATCATAATTTCTGCTTCTGGGCAGCAGGGTTGACAAAAAATTACCTGTAGAGCTTCCTCCCTCCTTTCCCACCCTATCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate