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TVIS30001216
Basic Information
VIS ID
TVIS30001216
Fusion event
HIV-RNASEH2B integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51527999/50953863 (Hg38)
End
51528634/50953863 (Hg38)
Orient
-
Location type
Intronic
Target gene
RNASEH2B
miRNAs that regulate target gene
hsa-mir-328-3p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-561-5p
;
hsa-mir-6778-5p
;
hsa-mir-1233-5p
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6878-5p
;
hsa-mir-766-5p
;
hsa-mir-6077
;
hsa-mir-4708-3p
;
hsa-mir-4481
;
hsa-mir-4745-5p
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-7703
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-542-3p
;
hsa-mir-661
;
hsa-mir-4252
;
hsa-mir-2277-3p
;
hsa-mir-6776-5p
;
hsa-mir-4793-3p
;
hsa-mir-3605-3p
;
hsa-mir-766-3p
;
hsa-mir-6742-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-665
;
hsa-mir-6771-5p
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-6787-3p
;
hsa-mir-6746-5p
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-216b-5p
;
hsa-mir-216a-5p
;
hsa-mir-34b-3p
Nearest miRNA
hsa-mir-15a/Upstream/904662; hsa-mir-1267/Downstream/394704;
Nearest TSS
ENST00000623511/Upstream/5799;
ENST00000614264/Downstream/157346;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/43408
,
chr13-CpG: 86/Downstream/268118
Target sequence
TATGTGAACATTTTCACAATTTAATGTTAAATAAAAAGCCCAGAACTGAGTATTATAATGCCAATGTTAAAGGCCACATATGTATTTATAATGCATGTATAAAACTAAGTAAGGACTGTTACCAAAATGCCATTTGCCAGGGTGAATGCTGAATGGTGAAATTATTAATTTTTATCATCATAATTTCTGCTTCTGGGCAGCAGGGTTGACAAAAAATTACCTGTAGAGCTTCCTCCCTCCTTTCCCACCCTATCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
L1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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