Basic Information
VIS ID
TVIS30001222
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
235370363/234461719 (Hg38)
End
235371225/234461719 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/1911146; hsa-mir-149/Downstream/3049212;
Nearest TSS
ENST00000437798/Upstream/7124; ENST00000629370/Downstream/34881;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/365207, chr2-CpG: 184/Downstream/34139
Nearby gene
ARL4C(No orient, 31323)
Target sequence
ATTTTAAACTTGTAATAGCAGAAATAGGAGAAATACAGGACTCACAAATTCATATATGAGTGTATGTGTAGGAGTTAATAACCAAAGGTTGAGTTTCTTTACAGTAGGATTTCTCTAGAACTTAAAAATCTAATTTCCCTGTTGTAGAGTTAACCCTTAAAATCAACCTGATGGAGAGCAGAAACATAACCACCACGATGGATGAACCAGTAAGAAGTGGCTATAACTTCTAAAGGGCTGAGCACAGCCCAGGAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate