Basic Information
VIS ID
TVIS30001224
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
60751894/59839335 (Hg38)
End
60752629/59839335 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/16943060; hsa-mir-10400/Downstream/1875453;
Nearest TSS
ENST00000518652/Upstream/237931; ENST00000531077/Downstream/210252;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/719148, chr8-CpG: 14/Downstream/334231
Nearby gene
CA8(No orient, 349529)
Target sequence
TACAGCATAGGGTCCTCTGAGAATGTGGACAGCTTGTGTAAACCACCTTGGCCTAATTGTACCTATTTAATTAGTTCTGTGTGTAGGAAGATAGTAACTATCAGTGATAATGACAATTTCTTCTCAACTTCAACTTTTTTTGGTTAATTCAGTTACATTCTAGATGTCTTTTCCCATTTTGAAGGTGACGTATAGCTTACAACATAGGAAGATAGAACACAAAAAAGCATACCTTTTATTTCACGTTCCATAAGG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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