Basic Information
VIS ID
TVIS30001225
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
116413098/115400870 (Hg38)
End
116413960/115400870 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/2757287; hsa-mir-10400/Downstream/1473858;
Nearest TSS
ENST00000518652/Upstream/1118734; ENST00000415088/Downstream/91351;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1968014, chr8-CpG: 33/Downstream/247335
Nearby gene
TRPS1(No orient, 7626)
Target sequence
GATACCGTATATAAAGATGTAACCCCTGAGCAAGCGAATTTTTAGAAATGTTTATGGATAAGGCCAAATTGACTTAGTCATCTTAGGAAATAGGAGATTAATAGATGCCTAGAAGATGCAGTACTCAACTCTTCGTACAGAATAATCTGCATAGGACTCTTAAAGGGCCAGCATTGGCTCTTGAATTTATAGTAAGATAGTAACATTTGAATTTATAGTAAGATAGTAAGACAGCATTGCTTGTTCTGGTTGTCT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate