Basic Information
VIS ID
TVIS30001226
Fusion event
HIV-chr4 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
146223628/145302476 (Hg38)
End
146224187/145302476 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/1958941; hsa-mir-1305/Downstream/1106107;
Nearest TSS
ENST00000502981/Upstream/122315; ENST00000514168/Downstream/37945;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/121573, chr4-CpG: 155/Downstream/178911
Nearby gene
OTUD4(No orient, 122796)
Target sequence
GGCACTAAGGAAATCTTTACAACATACACTTGCCATGGTATTGCAAGGTCTTTCTTTCTAGGGACCCAGACACTTCTTTAGTCAATGGGTTCTGGATCTGAAAATTGGCTCAGGGACAGGAACTGTAAAAAAGATCCTGAATTTTTATTTGGACAACCATTCTCAACTTCCTGCTTCTCTGGTCTTGCTTCGTTCTTACAACAAATGTTAAACAGCACCCTTGTTGCTGCCTATTTTACCCCTAGGGACAAACGT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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