Basic Information
VIS ID
TVIS30001228
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
58502207/57589648 (Hg38)
End
58502451/57589648 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/14693373; hsa-mir-10400/Downstream/4125140;
Nearest TSS
ENST00000518652/Upstream/96749; ENST00000518934/Downstream/156501;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/309323, chr8-CpG: 99/Downstream/404743
Nearby gene
LOC101929488(No orient, 224792)
Target sequence
GTCTCCATCTCTCTTCCAGAGCCTGAGCCCCCATTACATGAGAGGATTTCAAGAAATGTGAATTGACCTTCTGCCCCCACCTGTCTCCCAACCTGCAACATCCCCTGTTCTTTTTCTAATTTACTCCTTCAAGTGTCAAGTTTCAAATGTCACTTCCTCAGAAAGGCCTTTAATCAAATAATGTATAAGCGAGCATTCACTCAAGTTTATCTGTTACTTGTAAGTCTTCCTCTTCAAACCCCAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate