Basic Information
VIS ID
TVIS30001230
Fusion event
HIV-chr7 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
62128633/62668255 (Hg38)
End
62129542/62668255 (Hg38)
Orient
-
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/5263165; hsa-mir-10399/Downstream/952835;
Nearest TSS
ENST00000635602/Upstream/5218078; ENST00000418297/Downstream/386176;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/287358, chr7-CpG: 49/Downstream/385882
Target sequence
ATTTGCTTGGTAGATCTTCCTCCATCCTTTTATTTTGAGCCTATGTGTGTCTCTGCATGTGAGATGGGTCTCCTGAATACAACACACTGATGGGTCTTGACTCTTGATCCAATTTGCCAGTCTGTGTCTTTTAATTGGAGCATTTAGTCCATTTACATTTAAGGTTAATATTGGTTTGTGTGAATTTGATCCTGTTATTATGATGTTAGCTGGATATTTTGCTCATTAGTTGATCCAGTTTCTTCCTAGCCTTGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate