Basic Information
VIS ID
TVIS30001232
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
75685067/76464665 (Hg38)
End
75685711/76464665 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/2177308; hsa-mir-105-1/Downstream/454608;
Nearest TSS
ENST00000429181/Upstream/36941; ENST00000439435/Downstream/549618;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/35525, chrX-CpG: 71/Downstream/982804
Nearby gene
MAGEE1(No orient, 33321)
Target sequence
GTGGCCTTGAATGGTAATTAGTATTTCTATGATATCAGTTGTAATACCTTCTATTTTATTTCTAATTGAGCTTATTTAGATATTTTCTCTTATTTTCTTGGTTAATCTTACTAGTGTTTTATCAATTCTATTTATCTTTTCAAAGAACCAGCTTTTTGTTTCATTTATCTTTTGTGTTTTTGTTTTGTTTTGTTTTCATTTCATTTAGTTCTGGTTTGATCTTTGTTATTTCCTTTCTTCTGCTGGGTTTGGGTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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