Basic Information
VIS ID
TVIS30001235
Fusion event
HIV-chr18 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23592597/26012633 (Hg38)
End
23592711/26012633 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/1690887; hsa-mir-122/Downstream/578834;
Nearest TSS
ENST00000575820/Upstream/660443; ENST00000415576/Downstream/22432;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/662367, chr18-CpG: 122/Downstream/77374
Nearby gene
SS18(No orient, 3620)
Nearest cancer related gene
SS18(OG, No orient, 3620)
Target sequence
AGATGAAAAAGAAATCCTGAATGTTCTGAAAGGTTATCATTTTTGTTCTCTCCTAGGAATAATGATTTTCCTCCATTATTATTATTTTTATTTATTTATTTATTTTTTGAGACA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate