Basic Information
VIS ID
TVIS30001238
Fusion event
HIV-LOC101927550 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
98618737/99021114 (Hg38)
End
98618910/99021114 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
LOC101927550
Nearest miRNA
hsa-mir-10525/Upstream/139385; hsa-mir-10399/Downstream/388058;
Nearest TSS
ENST00000635602/Upstream/6496; ENST00000482799/Downstream/9481;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8678, chr7-CpG: 18/Downstream/14354
Target sequence
GGAATGCCATAAATGAGACCAGAAGTAGAGAGGCAAGGGCAGAAAGTATATTTAAAGAAAGTTCAACAGAAAACTGTTCATATTTGATTAAAAAAAAAATGTATCTACAAACCCAATTAGCATAACAAACTCTGGATAGGATAAGCTCAAGGAAACACACACCAAGACACTTC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate