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TVIS30001270
Basic Information
VIS ID
TVIS30001270
Fusion event
HIV-MCF2L2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
183078358/183360570 (Hg38)
End
183078539/183360570 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
MCF2L2
miRNAs that regulate target gene
hsa-mir-510-3p
;
hsa-mir-6818-3p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-4738-3p
;
hsa-mir-3923
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-1273e
;
hsa-mir-25-5p
;
hsa-mir-7160-5p
;
hsa-mir-658
;
hsa-mir-202-3p
;
hsa-mir-4500
;
hsa-mir-98-5p
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-6087
;
hsa-mir-219b-3p
;
hsa-mir-7162-3p
;
hsa-mir-1247-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-6888-5p
;
hsa-mir-302f
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-6883-5p
;
hsa-mir-6799-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-383-3p
;
hsa-mir-890
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-7703
;
hsa-mir-500a-3p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-542-3p
;
hsa-mir-661
;
hsa-mir-767-5p
;
hsa-mir-6776-5p
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-6742-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-508-5p
Nearest miRNA
hsa-let-7g/Upstream/6845419; hsa-mir-1224/Downstream/526230;
Nearest TSS
ENST00000440867/Upstream/49543;
ENST00000491676/Downstream/39923;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/105723
,
chr3-CpG: 126/Downstream/67069
Target sequence
GTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGAGTGACCCACCACGCCTGGCCTAGTACACTGTATGTTATTTTTCTAGGTGAGAAGAAACATCAGAAGTAGTTGAAGGCACAGGAAGAAGTGGATCCTCTAAGGATGAGGAGACATTCTCTCAAATGGCTTTTTTTTTTTGAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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