Basic Information
VIS ID
TVIS30001270
Fusion event
HIV-MCF2L2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
End
183078539/183360570 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7g/Upstream/6845419; hsa-mir-1224/Downstream/526230;
Target sequence
GTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGAGTGACCCACCACGCCTGGCCTAGTACACTGTATGTTATTTTTCTAGGTGAGAAGAAACATCAGAAGTAGTTGAAGGCACAGGAAGAAGTGGATCCTCTAAGGATGAGGAGACATTCTCTCAAATGGCTTTTTTTTTTTGAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate