Basic Information
VIS ID
TVIS30001272
Fusion event
HIV-NF2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
End
30023928/29626974 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-193b-3p ; hsa-mir-1229-3p ; hsa-mir-10a-5p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-185-3p ; hsa-mir-423-5p ; hsa-mir-762 ; hsa-mir-3184-5p ; hsa-mir-4486 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-5001-5p ; hsa-mir-5787 ; hsa-mir-6085 ; hsa-mir-6813-5p ; hsa-mir-1273e ; hsa-mir-4497 ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-6087 ; hsa-mir-219b-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-302f ; hsa-mir-4668-5p ; hsa-mir-31-5p ; hsa-mir-5681a ; hsa-mir-6779-5p ; hsa-mir-5589-3p ; hsa-mir-3922-5p ; hsa-mir-4312 ; hsa-mir-4696 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1273g-3p ; hsa-mir-7703 ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-3117-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-1228-5p ; hsa-mir-1253 ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-1285-3p ; hsa-mir-3187-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-345-3p ; hsa-mir-378g ; hsa-mir-4319 ; hsa-mir-4488 ; hsa-mir-4732-3p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-670-5p ; hsa-mir-6770-5p ; hsa-mir-6860 ; hsa-mir-7113-3p ; hsa-mir-1207-5p ; hsa-mir-1471 ; hsa-mir-3148 ; hsa-mir-3917 ; hsa-mir-4281 ; hsa-mir-4434 ; hsa-mir-4449 ; hsa-mir-4516 ; hsa-mir-4690-5p ; hsa-mir-4736 ; hsa-mir-4746-5p ; hsa-mir-4763-3p ; hsa-mir-4783-3p ; hsa-mir-4795-5p ; hsa-mir-542-3p ; hsa-mir-5703 ; hsa-mir-6165 ; hsa-mir-6510-5p ; hsa-mir-7150
Nearest miRNA
hsa-mir-1286/Upstream/1167026; hsa-let-7a-3/Downstream/380075;
Nearest cancer related gene
NF2(TSG, No orient, 0)
Target sequence
GGCCTTAAGGTATATATTTTACCCCTTTGGTGAAACATACTGATTTCCTCTCTCTAAAAATACCTTGGCAAGGAAATCTAAATCTCAAACAACCAAAGAAGAAAATTTTCCACAGAACAAAGGAGACTAGTAAGAAACAAATCACAGCACCTTGGGAAGCCACAAAATGGAGCTTTTAAACTCTGGTAAGTCTTTCAAAACCAAATGAATTACAGTTTTTTAGGGGAAAAAAAGGCCTTATGCTTGCAGTTTCTG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate