Basic Information
VIS ID
TVIS30001274
Fusion event
HIV-NR2C2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
End
15044138/15002000 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/4607438; hsa-let-7g/Downstream/494239;
Nearest cancer related gene
NR2C2(TSG, No orient, 0)
Target sequence
CTTCACAAAAAACTCTTCCTAAAATTAGAAGAAAACACTTCCCAATTCTGTGAGGCCAATATTACCTGATACTGAAACCAAAGACATCACAGGAAAAGAAAACTACAGACCAATATCTCTTATGAATAGAAACACAAACAATCCTCTACAAAACACTAGCAAACCAAATCCAGTGGTATATAAAGGATTATACACCACGAATAACTGGGGTTCATCCCAGGAAAGCAAGCTTGTTCAAATATGAAAATCAAACAG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate