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TVIS30001275
Basic Information
VIS ID
TVIS30001275
Fusion event
HIV-PHF21A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
46119180/46097629 (Hg38)
End
46119970/46097629 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHF21A
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-221-3p
;
hsa-mir-548c-3p
;
hsa-mir-7855-5p
;
hsa-mir-216a-5p
;
hsa-mir-129-5p
;
hsa-mir-1909-3p
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-4468
;
hsa-mir-6081
;
hsa-mir-6132
;
hsa-mir-6722-3p
;
hsa-mir-6754-5p
;
hsa-mir-6836-5p
;
hsa-mir-759
Nearest miRNA
hsa-mir-129-2/Upstream/405853; hsa-let-7a-2/Downstream/278773;
Nearest TSS
ENST00000527297/Upstream/5424;
ENST00000528480/Downstream/18949;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/174407
,
chr11-CpG: 65/Downstream/22199
Target sequence
GTTTTTTATTCTACTTAAAAGCCTTCCTGTAATTACCCTCTGGCCTCAAAGTCTTTTATTAGCTAGTGTGGCTCACATTTTTCAAGCATATAGAAGTTAATATGCACTGTTTTAGAACTTAGACACTACAACCACTGGTCAAGTAATAGATAATCAGTGTTTACTACACCCATCTGTGAATTGTGGATTTTTATTACTTCCATTTATTTATGTACAGTCTAAATCTTTGTAGATTTTAGCTAGTCATCTGGACTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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