Basic Information
VIS ID
TVIS30001291
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
99333113/98867557 (Hg38)
End
99333947/98867557 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1M
Nearest miRNA
hsa-mir-101-1/Upstream/821386; hsa-mir-11399/Downstream/1413684;
Nearest TSS
ENST00000473358/Upstream/205334; ENST00000425113/Downstream/136719;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/205402, chr1-CpG: 74/Downstream/136819
Nearby gene
PLPPR5(No orient, 22688)
Target sequence
GGGACCATGTGTTCATTTATATAGAACCACTACTCTAGTGCTGAAACTACAAAATAGGAGGCATTTATTAAAATATTTTCATATAAATAAATAATTTCATGACTCTTTAGTAATAAAGCATAAGGACTAAGAGGTAGGATTTGGAAAACAAAAAGAATTGAGTTCAAATTCCATATCTGATATTTTTAGCTGGGAAATTTTAAGCAAGTCAAATTACCTGCCTTGGCCTTAGTTTCTTCTTTGAAATATACTATT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate