Basic Information
VIS ID
TVIS30001293
Fusion event
HIV-chr3 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
40728626/40687135 (Hg38)
End
40729432/40687135 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/1548869; hsa-let-7g/Downstream/3427077;
Nearest TSS
ENST00000440867/Upstream/81708; ENST00000412811/Downstream/79072;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/71231, chr3-CpG: 153/Downstream/511536
Nearby gene
ZNF621(No orient, 147341)
Target sequence
GTTTCTTAACAAACCACCTGCATACCAATCTTCATCTCAAGGCCTGCATCTGTGGTGACCAGCTTAAGAAGGAAGGTTATAGTAGCTTTGTTATCATTTATTCAACAAACATTATTGAACTCCTTTAATATATCAGGTACTAACCCAGGGATCAAAAGTCAAACAGAAGCTAATTTCAGTCCTTATGAAGCTCACAAAAAAGTAAGGAGACAATAGAGGAGAACCAATAATACATTTTGTTAAGCAAGAGAGGCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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