Basic Information
VIS ID
TVIS30001295
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
192448362/191583636 (Hg38)
End
192448685/191583636 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/2450525; hsa-mir-1244-1/Downstream/15199598;
Nearest TSS
ENST00000437798/Upstream/172571; ENST00000491331/Downstream/94432;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/337422, chr2-CpG: 88/Downstream/94211
Nearby gene
NABP1(No orient, 94436)
Target sequence
GAGTGAAACAGTGCTTTTCCTTGACTCTGATTCTACTTTTGATAAGAAACTTCTCTGTCTGTTTGGGGGCTCAAGGATGATTTTAAGGCTCAGGCTGTCAGTGGCTTTTTAAGTCCAGGCTTATGTGGAACCCTACCCAAAGTTCTTTCACAAACGTAACTATTATCCGTTATTTCTTTCCTTGCTTCCTCAGCTTCATGCCTCTCTCACATGCACCCAATTTGATGCCAGCATCCCTGAAGTCATATGGTTTGG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate