Basic Information
VIS ID
TVIS30001297
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
60560035/59647476 (Hg38)
End
60560342/59647476 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/16751201; hsa-mir-10400/Downstream/2067312;
Nearest TSS
ENST00000518652/Upstream/46072; ENST00000531077/Downstream/402111;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/527289, chr8-CpG: 14/Downstream/526090
Nearby gene
TOX(No orient, 528268)
Target sequence
GTCCTGTTGTCTTCC:CCGTGAAGAGATAGCTTTTATCCTGAGTTGAGTTTGAGGCTGAGATCTATATGGTGGTGAGTTCAGATGAGCATCAGATAACTTAGTATCATCCTTGGAATAGTATGGAATGCAAGAAATCACTAGAAATTTGATCTTCCTCATGAGGTGATTCAGACTAGACAGCTAGAAATACTCACAGAACTGACTTAACAGGCTCTCAGAATAGCTTAACCTAGTATCATCTAGCTGAGGCATGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate