Basic Information
VIS ID
TVIS30001298
Fusion event
HIV-chr18 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
18519685/20939724 (Hg38)
End
18520266/20939724 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-3156-2/Upstream/6109482; hsa-mir-1-2/Downstream/743794;
Nearest TSS
ENST00000575820/Upstream/5775257; ENST00000579454/Downstream/15146;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/5608549, chr18-CpG: 113/Downstream/171255
Target sequence
GTGACTTGAATGCAGATATCACAAAGAAGTTTCTGAGAATGCTTCTGTCGAGATTTTATATGAAGATATTCCCGTTTCCAACGAAATCCTGAAATCTATCCAAATATCCCCTCGCAGATTCTACAAAAAGAGTGTTTCAAAACTGCTCTGTAAAAAGAAAGGTTCAACTCTGTTAGTTGAGTACACACATCACAAACAAGTTTCACAGAATGCTTCTTTCTAGCTTGTAGGGGAAGATATTCCCTTTATCACCAT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate