Basic Information
VIS ID
TVIS30001301
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
9326128/9358088 (Hg38)
End
9326462/9358088 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-1/Upstream/1231027; hsa-let-7f-2/Downstream/1960526;
Nearest TSS
ENST00000429181/Upstream/108168; ENST00000497555/Downstream/105207;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/15199, chrX-CpG: 183/Downstream/106702
Nearby gene
TBL1X(No orient, 105207)
Target sequence
GTTTCTCAACCTGTATTTTACTTTATTTTATATTGTTAGAGACAGAGTCTCACTGTGTCACCCAGGCTGGGGTGCAGTGGCACGATCATAGCTAACCACAGCCTTGAACTCCTGGATTCAAGTGATCCTCCTGCCTCAGCCGCCCGAATCACTGGGATCACAGGTGTGCACCACCGTGCCTAGCTTCAACCTGTATTTGTAACTATTTTTTGAGTTTATGGGGAATGCTATCTTTTTTTTAGTGAGACTATGAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate