Basic Information
VIS ID
TVIS30001303
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
35677799/35186896 (Hg38)
End
35678071/35186896 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/64132; hsa-let-7e/Downstream/158617;
Nearest TSS
ENST00000633603/Upstream/22861; ENST00000602003/Downstream/41833;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/31752, chr19-CpG: 34/Downstream/37824
Nearby gene
FXYD5(No orient, 17011)
Target sequence
GTGAGCCACCACACCTCATCACTGCAGCCACTATGGAAAACAGTCCAGTAGTTCCTCAAACTGTTAAAAATGCAGTCACCATTTGACCCAGCAATTTTATTCCTAAGAGAAATGAAAACTTATGTCCACATAATAACAAATACATAAGTTTATTTTCATATTATTCATAATAGCCAAAAGGTGAAAACAAAACCAAATATCTACAAACTGATGGAGGCATAAACAATATTTGGGGGGGCGGGGTCTGTAAAAAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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