Basic Information
VIS ID
TVIS30001304
Fusion event
HIV-LOC112268076 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
67692445/67924974 (Hg38)
End
67692931/67924974 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
LOC112268076
Nearest miRNA
hsa-mir-10392/Upstream/434659; hsa-let-7a-2/Downstream/107890;
Nearest TSS
ENST00000527297/Upstream/38384; ENST00000617449/Downstream/71006;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/118594, chr11-CpG: 76/Downstream/30189
Nearby gene
UNC93B1(No orient, 66126)
Target sequence
CACTCCAGCCTGGGCAACAGAGTGAGACTCTCTCCAAAAAGAAGGAAAAAAAAAGTATCTGGGCTGGTGGCATGCGCCTTTAGTCTCAGCTACTCTGAAGGCTGAGATGGGAGGATGGCTTGAGGCCAGGAGTAATTTGAGGCTGCAGTGAGCTATGATTGTGACACTGCACTCTAGCCTGGACTACAGAGCAAGACCCTGTCTCTTATACATACATACATGCATACATACATACATACATGCATACATACATAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate