Basic Information
VIS ID
TVIS30001305
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
9326118/9358078 (Hg38)
End
9326462/9358078 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-1/Upstream/1231017; hsa-let-7f-2/Downstream/1960536;
Nearest TSS
ENST00000429181/Upstream/108158; ENST00000497555/Downstream/105217;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/15189, chrX-CpG: 183/Downstream/106712
Nearby gene
TBL1X(No orient, 105217)
Target sequence
GTTTCTCAACCTGTATTTTACTTTATTTTATATTGTTAGAGACAGAGTCTCACTGTGTCACCCAGGCTGGGGTGCAGTGGCACGATCATAGCTAACCACAGCCTTGAACTCCTGGATTCAAGTGATCCTCCTGCCTCAGCCGCCCGAATCACTGGGATCACAGGTGTGCACCACCGTGCCTAGCTTCAACCTGTATTTGTAACTATTTTTTGAGTTTATGGGGAATGCTATCTTTTTTTTAGTGAGACTATGAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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