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TVIS30001307
Basic Information
VIS ID
TVIS30001307
Fusion event
HIV-ZBTB25 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
64955303/64488585 (Hg38)
End
64955520/64488585 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
ZBTB25
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-7977
;
hsa-mir-4804-3p
;
hsa-mir-138-2-3p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-4772-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-1304-3p
;
hsa-mir-6741-3p
;
hsa-mir-3180-5p
;
hsa-mir-498
;
hsa-mir-491-3p
;
hsa-mir-5195-3p
;
hsa-mir-145-5p
;
hsa-mir-4528
;
hsa-mir-4538
;
hsa-mir-4453
;
hsa-mir-100-3p
;
hsa-mir-548av-3p
;
hsa-mir-5089-5p
;
hsa-mir-4256
;
hsa-mir-7973
;
hsa-mir-4731-5p
;
hsa-mir-6778-3p
;
hsa-mir-4707-3p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-4750-3p
;
hsa-mir-150-5p
;
hsa-mir-7107-5p
;
hsa-mir-1234-3p
;
hsa-mir-7108-3p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-526b-5p
;
hsa-mir-4261
;
hsa-mir-494-3p
;
hsa-mir-4778-3p
;
hsa-mir-6736-3p
;
hsa-mir-3688-3p
;
hsa-mir-4694-3p
Nearest miRNA
hsa-mir-208a/Upstream/393460; hsa-mir-1185-1/Downstream/297041;
Nearest TSS
ENST00000550708/Upstream/21478;
ENST00000556818/Downstream/1948;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/22761
,
chr14-CpG: 203/Downstream/14664
Target sequence
TCACCCCAAACAGAAACTTTGTACCCATTAAGCAATAACTCCCCATCTCACCCTCTCAACCCCCAGAAACCGCTAATTTACTTTCTATCTCTATGAATTTGCCTATTCTAGATATTTTATATAATACTTGTCCTTTTGTGTCTGGCTTATTTTACTTAGCATGATATTTTCTGGGTTCTCCATGTTGTAGCATGTATCAGAACTTCCTTCTTTTTAT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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