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TVIS30001313
Basic Information
VIS ID
TVIS30001313
Fusion event
HIV-ZNF148 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
124972463/125253619 (Hg38)
End
124972859/125253619 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF148
miRNAs that regulate target gene
hsa-mir-203a-3p
;
hsa-mir-335-5p
;
hsa-mir-186-5p
;
hsa-mir-132-3p
;
hsa-mir-181a-5p
;
hsa-mir-93-5p
;
hsa-mir-425-5p
;
hsa-let-7b-5p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-513a-5p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-3681-3p
;
hsa-mir-369-3p
;
hsa-mir-5692a
;
hsa-mir-155-5p
;
hsa-mir-629-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-136-5p
;
hsa-mir-885-5p
;
hsa-mir-5680
;
hsa-mir-488-5p
;
hsa-mir-365a-3p
;
hsa-mir-365b-3p
;
hsa-mir-6505-5p
;
hsa-mir-6806-5p
;
hsa-mir-4765
;
hsa-mir-4693-3p
;
hsa-mir-4774-5p
;
hsa-mir-4490
;
hsa-mir-6824-3p
;
hsa-mir-6764-3p
;
hsa-mir-5586-3p
;
hsa-mir-514a-5p
;
hsa-mir-618
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-9-3p
;
hsa-mir-6775-3p
;
hsa-mir-1291
;
hsa-mir-7976
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-4484
;
hsa-mir-6768-3p
;
hsa-mir-548an
;
hsa-mir-4429
;
hsa-mir-320d
;
hsa-mir-320c
;
hsa-mir-320b
;
hsa-mir-320a
Nearest miRNA
hsa-let-7g/Upstream/102067; hsa-mir-12124/Downstream/536785;
Nearest TSS
ENST00000440867/Upstream/20338;
ENST00000610060/Downstream/39174;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/40716
,
chr3-CpG: 24/Downstream/103769
Target sequence
GATGTTACTAATAGGAAGATGTTAAATTTCACCAAATGTTTTCTACCTACCTACTGAGATAAAATTTCCCTCCTTAATTTGTTAATTAAGGGTGAATTTGATTTGCTGATATGTGAATATTAAGCCAGTTTTGATACTTGAAAAGTTGATGTTGTCATGATAAATTATATTTAAATACTGCTGGATCTGACAGTTAATACTCTACATAGAACTCTTAAACCCATGTTGATAAGACAGAAATAGGTCTGCAATTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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