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TVIS30001314
Basic Information
VIS ID
TVIS30001314
Fusion event
HIV-AASDHPPT integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
105953504/106082777 (Hg38)
End
105953819/106082777 (Hg38)
Orient
-
Location type
Intronic
Target gene
AASDHPPT
miRNAs that regulate target gene
hsa-mir-132-3p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-98-5p
;
hsa-mir-143-5p
;
hsa-mir-186-5p
;
hsa-mir-576-3p
;
hsa-mir-936
;
hsa-mir-3944-5p
;
hsa-mir-377-3p
;
hsa-mir-216b-3p
;
hsa-mir-507
;
hsa-mir-557
;
hsa-mir-8064
;
hsa-mir-409-3p
;
hsa-mir-221-5p
;
hsa-mir-190a-3p
;
hsa-mir-4477a
;
hsa-mir-4642
;
hsa-mir-4720-5p
;
hsa-mir-4799-3p
;
hsa-mir-5011-5p
;
hsa-mir-5588-5p
;
hsa-mir-8073
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-let-7f-2-3p
;
hsa-mir-4789-5p
;
hsa-mir-98-3p
;
hsa-let-7f-1-3p
;
hsa-let-7b-3p
;
hsa-let-7a-3p
;
hsa-mir-194-5p
;
hsa-mir-4666a-3p
;
hsa-mir-381-3p
;
hsa-mir-300
;
hsa-mir-7849-3p
;
hsa-mir-802
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-8069
;
hsa-mir-1322
;
hsa-mir-1272
;
hsa-mir-656-3p
;
hsa-mir-4517
;
hsa-mir-148a-5p
;
hsa-mir-4695-5p
;
hsa-mir-4417
;
hsa-mir-27a-5p
;
hsa-mir-2115-5p
;
hsa-mir-6837-3p
;
hsa-mir-6754-3p
;
hsa-mir-412-3p
;
hsa-mir-194-3p
;
hsa-mir-1228-3p
;
hsa-mir-449b-5p
;
hsa-mir-449a
;
hsa-mir-34c-5p
;
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-10392/Upstream/2232797; hsa-let-7a-2/Downstream/5264980;
Nearest TSS
ENST00000527297/Upstream/5012;
ENST00000534152/Downstream/8690;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/4688
,
chr11-CpG: 137/Downstream/934820
Target sequence
GTTTCTAAAACTACTTACAGGTTTTAAATCCCAAGTGCATTTAAAAAAAAAAGTCCAGCAAAGTTTATTTTAAAAATGTAAAGACGAACATGTAAAACCATAGGGGGAAAATTCTGGTCCTTTCCCAAATTTCAATCATAATTTTTATGTATTTTGTCTATTTTATTTTGCCTTACTTTGTAAATATGGTCACAAAACTAAACAATTCAAAAGTTACCCTTTATGCTTATCACTTCAAACACTTTTAATGGTAGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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