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Viral Integration Site DataBase
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TVIS30001316
Basic Information
VIS ID
TVIS30001316
Fusion event
HIV-ATF6 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
161787890/161818100 (Hg38)
End
161788121/161818100 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATF6
miRNAs that regulate target gene
hsa-mir-503-5p
;
hsa-mir-424-5p
;
hsa-mir-335-5p
;
hsa-mir-191-5p
;
hsa-mir-199a-5p
;
hsa-mir-552-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6871-5p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-7153-3p
Nearest miRNA
hsa-mir-101-1/Upstream/590839; hsa-mir-1182/Downstream/339007;
Nearest TSS
ENST00000473358/Upstream/51806;
ENST00000476437/Downstream/21975;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/67814
,
chr1-CpG: 28/Downstream/165726
Target sequence
ATTAGTCTAATTTCTTTGGGGAAGTGAGAGAGGTGGCAAAATTAAGTGCATAAAAAGCGCCAACCTATATTACATTGATTAGTATGAGTACACAGATGGTTGAATTACTAATTTCTATATATTTTGCAATGGACTTTAAAAAGTAAACACTCTAGAGTGTTCAATAACTCTTACTGAGACCAGTAAATAAAGTTAAAGAATGTAATCTATTTCCTTTTTTTTTTTTTTTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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