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TVIS30001321
Basic Information
VIS ID
TVIS30001321
Fusion event
HIV-CREBBP integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
3876194/3826193 (Hg38)
End
3877132/3826193 (Hg38)
Orient
+
Location type
Intronic
Target gene
CREBBP
miRNAs that regulate target gene
hsa-mir-324-3p
;
hsa-mir-1301-3p
;
hsa-mir-935
;
hsa-mir-769-5p
;
hsa-mir-125b-5p
;
hsa-mir-100-5p
;
hsa-let-7e-5p
;
hsa-mir-543
;
hsa-mir-4635
;
hsa-mir-218-5p
;
hsa-mir-33a-3p
;
hsa-mir-1264
;
hsa-mir-6507-3p
;
hsa-mir-4684-5p
;
hsa-mir-3143
;
hsa-mir-601
;
hsa-mir-4765
;
hsa-mir-942-5p
;
hsa-mir-1251-5p
;
hsa-mir-517-5p
;
hsa-mir-325
;
hsa-mir-628-3p
;
hsa-mir-6729-3p
;
hsa-mir-8079
;
hsa-mir-1245a
;
hsa-mir-5586-3p
;
hsa-mir-802
;
hsa-mir-2681-5p
;
hsa-mir-302c-5p
;
hsa-mir-5681b
;
hsa-mir-571
;
hsa-mir-5680
;
hsa-mir-6512-5p
;
hsa-mir-338-5p
;
hsa-mir-4517
;
hsa-mir-1252-3p
;
hsa-mir-219a-1-3p
;
hsa-mir-4268
;
hsa-mir-4641
;
hsa-mir-4264
;
hsa-mir-4797-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-4328
Nearest miRNA
hsa-mir-1225/Upstream/340724; hsa-mir-11401/Downstream/845125;
Nearest TSS
ENST00000527434/Upstream/13216;
ENST00000571169/Downstream/24128;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/94776
,
chr16-CpG: 208/Downstream/53289
Nearest cancer related gene
CREBBP
(TSG, No orient, 0)
Target sequence
CAGAGCCAGACCCAGTCTCGGCGGGCGGGGAGCAAGATGAATACATATCATGTAAAAGACACTTTCATTTATCCTGTTAAAATTGATTTCATTTAGTAAAAAACTATGAAGAGACAGATCTCCCACACTGAAGAAGTCTAAATAAATTATGTAGACACTTTGCCTAAAGAAGGTAGAATATAAACCCCCTATCCTTAAACATAGTGAGTCCTTCCAAAGAGGATGGCATGGAGGAGGGAAGCGGAGCATTACAGT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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