Basic Information
VIS ID
TVIS30001328
Fusion event
HIV-FYN integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
End
112074851/111753260 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/4969040; hsa-mir-1202/Downstream/7315787;
Nearest cancer related gene
FYN(OG, No orient, 0)
Target sequence
GGTTCTTTACAGATTTCAGTAATGCATTATCCAAAAAGGCCTCTCATAATACCTTTGGGAATAAGATAGGAAAATGTGGGCTAGATACTAGAACAATGAAGTGAATTATAATATTTAAGTGGGGCTGATTGGTGAGCTCAGGTCCACCTAGAAGGTGGTCTCAGGAGGCCTAAAATGGGGCTCTGAGCTCTTCAAAAACTTGTCAACATCTTAGATGAAGATATTGAAAATTTGTATGGTGAAATATTCAGATGG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate