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Viral Integration Site DataBase
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TVIS30001334
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
64584179
64181180
64381440
64165517
64356259
64364311
64387687
64354573
64357467
64362408
64362702
64326801
64327000
64368201
64368400
64337902
64338051
64369222
64369371
64374848
Basic Information
VIS ID
TVIS30001334
Fusion event
HIV-PCLAF integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
64667047/64374848 (Hg38)
End
64667154/64374848 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
PCLAF
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-124-3p
;
hsa-mir-122-5p
;
hsa-mir-181a-5p
;
hsa-mir-26b-5p
;
hsa-mir-1227-3p
;
hsa-mir-466
;
hsa-mir-539-5p
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-4705
;
hsa-mir-4698
;
hsa-mir-8063
;
hsa-mir-3156-5p
;
hsa-mir-551b-5p
;
hsa-mir-335-3p
;
hsa-mir-4715-3p
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-5696
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-661
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-149-5p
;
hsa-mir-153-5p
;
hsa-mir-1250-3p
;
hsa-mir-6504-3p
;
hsa-mir-455-5p
;
hsa-mir-4438
;
hsa-mir-7703
;
hsa-mir-6807-5p
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-1273g-3p
;
hsa-mir-3934-5p
;
hsa-mir-512-5p
;
hsa-mir-552-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6872-3p
;
hsa-mir-183-5p
Nearest miRNA
hsa-mir-10393/Upstream/503829; hsa-mir-11181/Downstream/387539;
Nearest TSS
ENST00000557528/Upstream/1067;
ENST00000558442/Downstream/6307;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/18524
,
chr15-CpG: 25/Downstream/12860
Nearest cancer related gene
PCLAF
(OG, No orient, 0)
Target sequence
GTGTGCAACCTTTAAAAAAAAGTTTCCGAGTTTCATCCGTTGTATTTCATGAATATCTCATTCCTTTTTTCCTTTTTTTCTTTCTTTCTTCCTTTTTTTTTTTTTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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