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TVIS30001334
Basic Information
VIS ID
TVIS30001334
Fusion event
HIV-PCLAF integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
64667047/64374848 (Hg38)
End
64667154/64374848 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
PCLAF
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-124-3p
;
hsa-mir-122-5p
;
hsa-mir-181a-5p
;
hsa-mir-26b-5p
;
hsa-mir-1227-3p
;
hsa-mir-466
;
hsa-mir-539-5p
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-4705
;
hsa-mir-4698
;
hsa-mir-8063
;
hsa-mir-3156-5p
;
hsa-mir-551b-5p
;
hsa-mir-335-3p
;
hsa-mir-4715-3p
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-5696
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-661
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-149-5p
;
hsa-mir-153-5p
;
hsa-mir-1250-3p
;
hsa-mir-6504-3p
;
hsa-mir-455-5p
;
hsa-mir-4438
;
hsa-mir-7703
;
hsa-mir-6807-5p
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-1273g-3p
;
hsa-mir-3934-5p
;
hsa-mir-512-5p
;
hsa-mir-552-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6872-3p
;
hsa-mir-183-5p
Nearest miRNA
hsa-mir-10393/Upstream/503829; hsa-mir-11181/Downstream/387539;
Nearest TSS
ENST00000557528/Upstream/1067;
ENST00000558442/Downstream/6307;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/18524
,
chr15-CpG: 25/Downstream/12860
Nearest cancer related gene
PCLAF
(OG, No orient, 0)
Target sequence
GTGTGCAACCTTTAAAAAAAAGTTTCCGAGTTTCATCCGTTGTATTTCATGAATATCTCATTCCTTTTTTCCTTTTTTTCTTTCTTTCTTCCTTTTTTTTTTTTTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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