Basic Information
VIS ID
TVIS30001361
Fusion event
HIV-TRA2B integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.2
Reference genome
End
185649516/185930887 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7g/Upstream/162983; hsa-mir-1248/Downstream/855785;
Target sequence
GTGACCCACCTCTTCTAAGGGGAAGCTACGGTATTTTATCAGTAATCCTAGTCAATCAGCTGAAATAGGCATTAAACAGAAACAGAATTTGAAAAACCATCCCTGTGTATTTAGCAAATATGCATCTTAAATTTAGGGCCCAAATGCTCACAGATTTCCACTAGTGCCATATGGAAAAAACTAACACACTAATGCCAAAGGGAACTATTTTGTTCAATGCTTTGTTTGGATTTTGGGGGTTTGGTTCCATAACCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate