Basic Information
VIS ID
TVIS30001364
Fusion event
HIV-USPL1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
31211307/30637170 (Hg38)
End
31211999/30637170 (Hg38)
Orient
-
Location type
Intronic
Target gene
USPL1
miRNAs that regulate target gene
hsa-mir-324-5p ; hsa-mir-320a
Nearest miRNA
hsa-mir-2276/Upstream/6474666; hsa-mir-1267/Downstream/9026864;
Nearest TSS
ENST00000623511/Upstream/19233; ENST00000479597/Downstream/76308;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/19118, chr13-CpG: 57/Downstream/36881
Target sequence
CTTACCTAATGTGCATCTAAGCTGGGGCTGAAGGCTAATAAAAATTTCATCTCTAACTTCATTCAGACAGGTCTCTATCTCTGCAAATATTTCTGAGGTAAGTTTTTTACAATCTCCATCTAAGAAAATACAGAGAACATTATCAATTCCTCATCAATGTATATCTTCCCACAGAAAACTGACACATTCCCAAGAATGAAAGCTGAGTCAGTAAGTTTTGCAAACAGACAAAAAGCAAAACACAAAATTTCCTTA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate