Basic Information
VIS ID
TVIS30001367
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
38728331/40572079 (Hg38)
End
38729271/40572079 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/378416; hsa-mir-10226/Downstream/945085;
Nearest TSS
ENST00000595228/Upstream/6607; ENST00000619697/Downstream/59682;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/128025, chr17-CpG: 69/Downstream/75613
Nearby gene
CCR7(No orient, 6595)
Target sequence
GGCAGTAATAAACAGCCTACCAACCAAAAAAAGTCCAGGACCAGATGGATTCACAGCTGAATTCCACCAGATGTACAGAAAAGAGTACCATTCCTACGGAAACTACTCAAAAAAATTGAAAAGGAGAGACTCCTTCCTAACTCATTCTGTGAGGCCAGCATCATCCTGATACCAAAACCTGGCAGAAATATAACAAAAAAAGAAAACTTCAGGCCATTATCCTTGATGAACATTGAGCAAAAATCCTCAACAAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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