Basic Information
VIS ID
TVIS30001372
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
172399534/172972531 (Hg38)
End
172400490/172972531 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5G
Nearest miRNA
hsa-mir-10397/Upstream/57373; hsa-mir-12118/Downstream/331199;
Nearest TSS
ENST00000502646/Upstream/12766; ENST00000517669/Downstream/11226;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/12432, chr5-CpG: 33/Downstream/11244
Nearby gene
RPL26L1(No orient, 2760)
Target sequence
TAATCCCAGCACTTTGGGAGCCTGAGGTGGAAGGATCGCTGGAGCCCAGGAGTTTCAGACCAGCCTGCGTAACATAGTGAGACCCCATATCGACAAAATAATTTAAAAACTAGCCAGGTGTGGTGGCCCATGCCTGTAGTCCCAGCTACCCAGGAGGCTGAGGTGGGGAGGATTGTTTGAACTCAGAAGGTCAAGATTGCAGTGAGCCATGATGACATTGCACTCTAGCCCGGGCAACAGAGCGGAACCCTGCCT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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