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VISDB
Viral Integration Site DataBase
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TVIS30001377
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
89724136
89926529
90296908
89984656
89988721
89997029
90000167
89976137
89979084
90003106
90005275
89988882
89991035
90008200
90009910
89974555
89975782
89971041
89971571
90007016
90007409
89970601
89970801
90000302
90000451
90010522
Basic Information
VIS ID
TVIS30001377
Fusion event
HIV-BACH2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
90720241/90010522 (Hg38)
End
90721131/90010522 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6G
Target gene
BACH2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-29c-3p
;
hsa-mir-615-3p
;
hsa-mir-8064
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-6083
;
hsa-mir-5011-5p
;
hsa-mir-656-3p
;
hsa-mir-410-3p
;
hsa-mir-3942-3p
;
hsa-mir-1324
;
hsa-mir-8485
;
hsa-mir-6797-3p
;
hsa-mir-6076
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-6749-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-2355-5p
;
hsa-mir-15b-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-6832-3p
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-5695
;
hsa-mir-3145-5p
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-4791
;
hsa-mir-3201
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-142-5p
Nearest miRNA
hsa-mir-10398/Upstream/11471213; hsa-mir-1202/Downstream/302220;
Nearest TSS
ENST00000381078/Upstream/1695;
ENST00000569865/Downstream/207723;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/122588
,
chr6-CpG: 227/Downstream/284554
Target sequence
TAGACAAACATAAAAATAGTAAAAGACAGAGTCCATAAATAGATTCATACATGTAAAAACAACTGATTTTCAGTAAAAATACAAAGGTAATTCAGGAGAGAAAAGAGTATTTTTAACAATGCTGCGGGAATGATTGGATATTCCTATGCAAAAGGAAAAAAAGAACCTCAATCCATACCTGTTACCTACACAAAAATTAACTCAAAATGGGCCATAGACCTAAATGTAAGGGCTAAAAAAATAACACTTCTAGCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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