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TVIS30001379
Basic Information
VIS ID
TVIS30001379
Fusion event
HIV-C18orf25 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
43841288/46261325 (Hg38)
End
43842234/46261325 (Hg38)
Orient
-
Location type
Intronic
Target gene
C18orf25
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-183-5p
;
hsa-mir-221-5p
;
hsa-mir-656-3p
;
hsa-mir-3128
;
hsa-mir-4795-3p
;
hsa-mir-8073
;
hsa-mir-142-3p
;
hsa-mir-5589-3p
;
hsa-mir-190a-3p
;
hsa-mir-1277-5p
;
hsa-mir-3613-3p
;
hsa-mir-5011-5p
;
hsa-mir-570-3p
;
hsa-mir-152-3p
;
hsa-mir-222-3p
;
hsa-mir-3152-5p
;
hsa-mir-4774-3p
;
hsa-mir-6514-3p
;
hsa-mir-6894-3p
;
hsa-mir-4799-5p
;
hsa-mir-661
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-126-5p
;
hsa-mir-660-5p
;
hsa-mir-1273d
;
hsa-mir-500a-3p
;
hsa-mir-767-5p
;
hsa-mir-410-3p
;
hsa-mir-141-3p
;
hsa-mir-200a-3p
;
hsa-mir-510-3p
;
hsa-mir-4263
;
hsa-mir-5571-5p
;
hsa-mir-708-3p
;
hsa-mir-7844-5p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ae-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-3064-3p
;
hsa-mir-155-3p
;
hsa-mir-5581-3p
;
hsa-mir-1283
;
hsa-mir-7853-5p
;
hsa-mir-105-5p
Nearest miRNA
hsa-mir-1-2/Upstream/1291159; hsa-mir-122/Downstream/1119171;
Nearest TSS
ENST00000575820/Upstream/87239;
ENST00000590330/Downstream/65484;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/86187
,
chr18-CpG: 65/Downstream/72057
Target sequence
AGAGAACTGCCTTGTTAGCAAGTCACACCAAGAGTTCACTGAAATAAAATTGTTTCAGAAACACTGACAGTTTGAATTCCACAGTCCAGTCAAATGATAGAATTGTGAACCTCCAGGCCAAAACACTAAGTTCTGACTCAAATGAGAGGAAGGCAGGCAACTCATGTGATCAATGCTATGTCCTCTCATCTAAACTTCCTGACCAGCCCTCAGGTAGCTTATGTGAGAAGTAACAAGTGGCATGAGTCTAGTCAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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