Basic Information
VIS ID
TVIS30001379
Fusion event
HIV-C18orf25 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
End
43842234/46261325 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1-2/Upstream/1291159; hsa-mir-122/Downstream/1119171;
Target sequence
AGAGAACTGCCTTGTTAGCAAGTCACACCAAGAGTTCACTGAAATAAAATTGTTTCAGAAACACTGACAGTTTGAATTCCACAGTCCAGTCAAATGATAGAATTGTGAACCTCCAGGCCAAAACACTAAGTTCTGACTCAAATGAGAGGAAGGCAGGCAACTCATGTGATCAATGCTATGTCCTCTCATCTAAACTTCCTGACCAGCCCTCAGGTAGCTTATGTGAGAAGTAACAAGTGGCATGAGTCTAGTCAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate