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TVIS30001380
Basic Information
VIS ID
TVIS30001380
Fusion event
HIV-CCSAP integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
229475914/229340167 (Hg38)
End
229476778/229340167 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
CCSAP
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-335-5p
;
hsa-mir-221-3p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-29b-3p
;
hsa-mir-92a-3p
;
hsa-mir-520a-5p
;
hsa-mir-525-5p
;
hsa-mir-3180-5p
;
hsa-mir-5701
;
hsa-mir-2053
;
hsa-mir-340-5p
;
hsa-mir-654-5p
;
hsa-mir-541-3p
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-608
;
hsa-mir-4651
;
hsa-mir-6721-5p
;
hsa-mir-5590-3p
;
hsa-mir-142-5p
;
hsa-mir-6782-5p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-8087
;
hsa-mir-4311
;
hsa-mir-186-5p
;
hsa-mir-3133
;
hsa-mir-510-3p
;
hsa-mir-616-3p
;
hsa-mir-508-3p
;
hsa-mir-4317
;
hsa-mir-203a-3p
;
hsa-mir-513b-3p
Nearest miRNA
hsa-mir-101-1/Upstream/878015; hsa-mir-1182/Downstream/1679661;
Nearest TSS
ENST00000473358/Upstream/20764;
ENST00000417605/Downstream/466;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/68785
,
chr1-CpG: 129/Downstream/1995
Target sequence
GTATTTAAAACCATCCACTTAAAAACCAGGATATTTAATCTTGTGCAAGCAACACAGGAGTCAAGAGGGCCTTACGGGTAGGAGCAAAACAAAAGATGCTGCGATTGAGTCCTGAAAGCAGAAAACATCCTTTCTTCTTCCTGATGCCTAAACCAGAAACGTTAGCAGGGAAGAAATAACTGAGAGGACGCTATATTTAAGGAAACCAAAATAATCATGAACTCAGAGCTTACCTGAGCTGGTAAATACAGGCAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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