Basic Information
VIS ID
TVIS30001384
Fusion event
HIV-FBXW7 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
End
153344150/152422307 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/4639639; hsa-mir-1305/Downstream/67020;
Nearest cancer related gene
FBXW7(TSG, No orient, 0)
Target sequence
GTAAATAATCAGTCAAATCTACACTACGAAAAGTCAGATCAAACATAAATTTTAAGAAAAAGAAAAGAATGAAAAATAAACCTGTAGATTAAAAGAGACTGAATAGAAGTAGCAACTCTTCTTAAAAATGGTCAAGATTAAATAATAGTTATCTAGGGAGGCTTACTTAGCTGATAAAGTGATAAATACAGGATGTAATTAAGAATAATTTAAAAGAAGTGAGTTACTTAGAGGAAGGGAAGGGGCTATGACTGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate