Basic Information
VIS ID
TVIS30001385
Fusion event
HIV-FMN2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
240357839/240194539 (Hg38)
End
240358710/240194539 (Hg38)
Orient
-
Location type
Intronic
Target gene
FMN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-4738-3p ; hsa-mir-374c-3p ; hsa-mir-4282
Nearest miRNA
hsa-mir-101-1/Upstream/2723348; hsa-mir-3123/Downstream/937733;
Nearest TSS
ENST00000473358/Upstream/14895; ENST00000441342/Downstream/41232;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/100776, chr1-CpG: 48/Downstream/13020
Target sequence
GGAACATTAGACAACACGGCAGCTCTATGCCTGGAGGCAATTTCGAACAGTAAAACCAACAAGAAAAAGCACAAAAACATGAAAAAACAGCCACAAAAACACTCTTATTTACAGAATGAGAGCTGAAAGAAGAAAGCAGAGCTTCACCTCATTCAACATCAGCTGGGAAAGTCCACGTCAAGCAACTCAAATTTCTTGCCACTTGGAGCGTGTTTGTGATTGGCCATGAAAGCACCATATGAATATGATTTGGGG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate