Basic Information
VIS ID
TVIS30001386
Fusion event
HIV-FRG1BP integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
29624145/30389469 (Hg38)
End
29624975/30389469 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
FRG1BP
Nearest miRNA
hsa-mir-103a-2/Upstream/4181191; hsa-mir-1-1/Downstream/1217717;
Nearest TSS
ENST00000382410/Upstream/27739; ENST00000400552/Downstream/868195;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/11788, chr20-CpG: 38/Downstream/94655
Target sequence
TATTCATTAAAATTTTTAGTATCTGTCTTAAACCCATGGTAATTTTGATATAAAAAATGAAATAGCTTTTTTGAAAAGTAGATTTTGTGATCTACTTTTAGTGGATTTCCTATCAATATATAATGCTAGGCTGGAAGAAAGATATGTAAGTTAAAAAATGAAGATTAATAATTTCACACACCAAGTAAGATAGATTAAAAAATAAATCAAATACTACAAAACCTTGTTCACTGTTGCTATGATATTTAAACTCAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate