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Viral Integration Site DataBase
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TVIS30001388
Basic Information
VIS ID
TVIS30001388
Fusion event
HIV-GPBP1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
56552788/57256961 (Hg38)
End
56552879/57256961 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
GPBP1
miRNAs that regulate target gene
hsa-mir-484
;
hsa-mir-365a-3p
;
hsa-mir-25-3p
;
hsa-mir-539-5p
;
hsa-mir-3646
;
hsa-mir-584-5p
;
hsa-mir-1283
;
hsa-mir-4744
;
hsa-mir-583
;
hsa-mir-1276
;
hsa-mir-4311
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-4660
;
hsa-mir-383-3p
;
hsa-mir-4761-5p
;
hsa-mir-646
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-4477a
;
hsa-mir-6758-3p
;
hsa-mir-1252-3p
;
hsa-mir-126-5p
;
hsa-mir-216a-5p
;
hsa-mir-1281
;
hsa-mir-150-5p
;
hsa-mir-1915-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-4279
;
hsa-mir-4421
;
hsa-mir-4485-5p
;
hsa-mir-4726-3p
;
hsa-mir-4757-5p
;
hsa-mir-498
;
hsa-mir-5571-5p
;
hsa-mir-5699-3p
;
hsa-mir-6744-3p
;
hsa-mir-6748-3p
;
hsa-mir-6764-5p
;
hsa-mir-6778-3p
;
hsa-mir-6787-3p
;
hsa-mir-6814-5p
;
hsa-mir-6840-3p
;
hsa-mir-6878-3p
Nearest miRNA
hsa-mir-10397/Upstream/1748035; hsa-mir-103a-1/Downstream/1273082;
Nearest TSS
ENST00000502646/Upstream/8099;
ENST00000506106/Downstream/138099;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/82267
,
chr5-CpG: 157/Downstream/1202546
Target sequence
GACTTCTTAAGTTATATACATATAAATACTCATATTAGTTGAATTCAATAATATGGGGCAGTGATAGTTTTTGTTTTTGTTTTTTTTTTGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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