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TVIS30001389
Basic Information
VIS ID
TVIS30001389
Fusion event
HIV-HMBOX1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
28778687/28921170 (Hg38)
End
28779107/28921170 (Hg38)
Orient
-
Location type
Intronic
Target gene
HMBOX1
miRNAs that regulate target gene
hsa-mir-30c-1-3p
;
hsa-mir-335-5p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-187-5p
;
hsa-mir-221-3p
;
hsa-mir-222-3p
;
hsa-mir-106b-5p
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-302c-3p
;
hsa-mir-302d-3p
;
hsa-mir-372-3p
;
hsa-mir-373-3p
;
hsa-mir-20b-5p
;
hsa-mir-520e
;
hsa-mir-520a-3p
;
hsa-mir-526b-3p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-519d-3p
;
hsa-mir-520d-3p
;
hsa-mir-302e
;
hsa-mir-548t-5p
;
hsa-mir-548v
;
hsa-mir-4501
;
hsa-mir-5580-3p
;
hsa-mir-548az-5p
;
hsa-mir-561-5p
;
hsa-mir-6830-5p
;
hsa-mir-802
;
hsa-mir-7-2-3p
;
hsa-mir-7-1-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-548n
;
hsa-mir-1238-3p
;
hsa-mir-670-3p
;
hsa-mir-3124-3p
;
hsa-mir-342-3p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-6892-3p
;
hsa-mir-216b-3p
;
hsa-mir-8087
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-29b-2-5p
;
hsa-mir-659-3p
Nearest miRNA
hsa-mir-124-1/Upstream/415988; hsa-mir-10400/Downstream/1036102;
Nearest TSS
ENST00000518652/Upstream/29854;
ENST00000518080/Downstream/42693;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/204847
,
chr8-CpG: 71/Downstream/150384
Target sequence
AGTATCTCGTAATCATGTTGGTTCATTTGGTCAACCATATCTACTAATACTTTGTGGTATTATTGGTAGTATTCATTCTTGCCTATTTTACTTACATGTAGAGAAGCTTTATTAAAATCTTTCTCAAGTCTACAGGTTTCCTTTATACAGTATATTCACTACATGACAAACTAAAAATAACAGGTCATAATCCATCATCCTGATATCAAGTGATGGTCAAACGTCTATGGAAATATTTTTGGTTTAGGTATGATT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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