Basic Information
VIS ID
TVIS30001395
Fusion event
HIV-KCTD13 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
29925377/29914056 (Hg38)
End
29925774/29914056 (Hg38)
Orient
+
Location type
Intronic
Target gene
KCTD13
Nearest miRNA
hsa-mir-1225/Upstream/314791; hsa-mir-11401/Downstream/589863;
Nearest TSS
ENST00000527434/Upstream/1686; ENST00000450909/Downstream/9181;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/12174, chr16-CpG: 75/Downstream/11661
Target sequence
CGACCTCAGGTGATCCACTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGACGTGAGCCACAGCGCCGGGCCCCTCCATTGTCTTTTATGACCTAGGTCTGTTGGTCCTATCCAGTGAGGAAGGAGATGACACACAGGAACGAGCACCAGGGGACGAGAATCATCAGGCTGCCTTGGTGGCTGGCTCCACAGGCCACCGCTGGCTCTCAGTGATTTCCCCCCTCCCACATGCCAAATATACTCACCACCTTCCA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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