Basic Information
VIS ID
TVIS30001400
Fusion event
HIV-NSD1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
End
176687328/177260154 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/630654; hsa-mir-1229/Downstream/2538124;
Nearest cancer related gene
NSD1(OG, No orient, 0)
Target sequence
AATCATTAATTCGGGACATCATTTCCTGAATGGCAGATGAATAGTATCATTTCTAATATTTTTTCCAGTGGCAATATGATGAAAAGTATTTTTGTTCCAATTAAAACATTGATTTAATCCCTTTTTAGACTACAAATAGAGGAAGAAATGATTTCTTACCTTCTGAGCACACA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate