Basic Information
VIS ID
TVIS30001402
Fusion event
HIV-NSMCE2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
End
126274779/125262283 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12123/Upstream/440225; hsa-mir-10400/Downstream/2533679;
Target sequence
GCGTGGTGGCAGGTGCCTATAGTCCCAGCTACTTGGGAGACTGAGGCAGGAAATGGCATGGACCTGGGAGGCAGAGCTTGCAGTGAGCAGAGATCGCGCCACTGCATTCCAGCCTGGGAGACAGAGTGAGACTCCCTCTCAAAAAATAAATAAATAAATAGTATACAATTTTGTGAAAGTATATGAGTCAAACTTTCCTTTAGTTTGCCATTCATTCATTCATCCATTTATTAGTATTCATCCATTTATTGTTC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate