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TVIS30001422
Basic Information
VIS ID
TVIS30001422
Fusion event
HIV-TRIM2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
154117878/153196726 (Hg38)
End
154118405/153196726 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRIM2
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-181c-5p
;
hsa-mir-335-5p
;
hsa-mir-130b-3p
;
hsa-mir-181a-5p
;
hsa-mir-10a-5p
;
hsa-mir-21-5p
;
hsa-mir-19b-3p
;
hsa-mir-186-5p
;
hsa-mir-10b-5p
;
hsa-mir-3190-3p
;
hsa-mir-493-5p
;
hsa-mir-574-5p
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-6867-5p
;
hsa-mir-223-5p
;
hsa-mir-5690
;
hsa-mir-511-3p
;
hsa-mir-5011-5p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-655-3p
;
hsa-mir-374c-5p
;
hsa-mir-410-3p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-6079
;
hsa-mir-411-5p
;
hsa-mir-3117-3p
;
hsa-mir-1258
;
hsa-mir-671-5p
;
hsa-mir-6828-5p
;
hsa-mir-3681-5p
;
hsa-mir-6849-5p
;
hsa-mir-1244
;
hsa-mir-1197
;
hsa-mir-504-5p
Nearest miRNA
hsa-mir-12113/Upstream/660210; hsa-mir-1305/Downstream/5932076;
Nearest TSS
ENST00000502981/Upstream/43608;
ENST00000496978/Downstream/7720;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/42833
,
chr4-CpG: 51/Downstream/26156
Target sequence
CACAACCCATTAAGGAGGTGAAAAGTTCTAAACTCATTCCATTAAACTTACTACCTGGAAGCTCCATATTTATTATTCTACATAATTTCTTCTTATTTCTTTGAGAAAGAAAGTGGTGGCAAGGCCTAAAGTCAGTTTCATATGTAGTCAGACAGTGAAGAAGATGCTGCTAACCACACATCAACACAGTGTGGACTTCTGTCTTTCCAAACATGCCAATGGGTTTTCTATAAGCCTCCTACATTTTTTTGCTCG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
R1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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