Basic Information
VIS ID
TVIS30001425
Fusion event
HIV-ULK4 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
41628248/41586757 (Hg38)
End
41629219/41586757 (Hg38)
Orient
+
Location type
Intronic
Target gene
ULK4
Nearest miRNA
hsa-mir-12127/Upstream/2448491; hsa-let-7g/Downstream/2527455;
Nearest TSS
ENST00000440867/Upstream/308606; ENST00000418790/Downstream/268154;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/386617, chr3-CpG: 17/Downstream/304360
Target sequence
GTTTCTTCAATATCAGAAAGAAAGAAAAAGAAGGAAAAGATGAAAAGAACTTAAAAGATGTACTATCAATGTGAATTTATTCAAATTAACTGTAAAAAATCATTTAAAAGACATTGAAAATTTGAACATTGACTGGATATTTGATAGTATTAATAAATTATTAATACTTAGGGGCAAAAAACACACCACCACCAGCCATTTATTATCTTAGTTTCTGTAGGTCAGAATTCAAGGCAGGCTCAACGGGTTCTCTAC
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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